Biology-driven discovery

Precision Single-Domain Antibody Therapeutics
for Immuno-Oncology and Complex Targets

AI-assisted biology-driven innovation with real-world impact. Advancing next-generation sdAb therapeutics through biology-aware discovery and data-driven antibody design.

3 Active programs
2 Discovery platforms
IO Lead therapeutic focus

Designed around the biology that matters.

mAbGenEx is built around PrecinAb™, a biology-aware antibody discovery platform. Instead of generating large antibody panels and hoping biology cooperates, we begin by identifying the epitope most likely to deliver specificity, safety, and functional impact.

Epitope-first strategy

Prioritizes the right binding region before costly discovery and engineering cycles.

AI + deep biology

Combines ML-guided design, structural logic, and experimental validation.

Translational intent

Focused on complex target biology, solid tumors, and programs where precision matters early.

Focused programs across tumor microenvironment modulation, antivenom innovation, and neglected tropical disease diagnostics.

Therapeutics

MGX-101
sdAb

Solid Tumors

Target: CCR8
Lead immuno-oncology program targeting TME/Treg biology.

  • Differentiation: First in Class / Novel MoA
DiscoveryPreclinicalIND
MGX-102
sdAb

Anti-snake Venom

Targets: PLA2, Btx
Next-gen monoclonal antivenom, moving beyond polyclonal approaches.

  • Differentiation: Monoclonal sdAb Cocktail
DiscoveryPreclinicalIND

Diagnostics

MGX-103
sdAb

NTD Diagnostic

Indication: Lymphatic Filariasis
Single-domain antibody-enabled diagnostic program for neglected tropical disease detection.

  • Differentiation: High-sensitivity sdAb detection
DiscoveryPreclinicalLaunch

Two Complementary Discovery and Design Engines.

PrecinAb™ and OptinAb™ work together to connect in-Silico precision with experimental screening and developability.

PrecinAb™

Precision Antibodies Redefined

Biology-Aware Antibody Discovery

Identifies the right target, epitope, and antibody concepts using biological insight and computational design.

  • Epitope-first strategy
  • Functional biology prioritization
  • Precision candidate generation
PrecinAb Workflow
OptinAb Workflow
OptinAb™

Optimized Antibodies

Experimental Optimization Platform

Converts promising antibody concepts into optimized therapeutic leads through advanced screening and engineering.

  • Natural repertoire-inspired libraries
  • Selectivity-focused screening
  • Affinity and developability optimization
Suresh Chintalapati
Suresh Chintalapati, PhD, MBA
Founder, CEO and Chairman

With over 25 years of experience in molecular biology, immunology, and biotechnology leadership, he is dedicated to translating cutting-edge science into innovative healthcare solutions with global impact.

LinkedIn
Lakshmipathi Khandrika
Lakshmipathi Khandrika, PhD
Director R&D

With over 22 years of experience in molecular biology, cell biology, and oncology research, he is committed to translating scientific discoveries into impactful healthcare innovations.

LinkedIn
Satyamurthy Kundharapu
Satyamurthy Kundharapu, PhD
Senior Scientist

With over 15 years of experience in structural biology, protein chemistry, and therapeutic antibody engineering, he is committed to translating scientific innovation into next-generation biologics.

LinkedIn
Aswani Valiveti
Aswani Valiveti, PhD, MBA
Advisory Board Member

Advises mAbGenEx on innovation positioning and strategic partnerships across life science research and enterprise formation.

LinkedIn
Sadanand Vodala
Sadanand Vodala, PhD
Advisory Board Member

Translational medicine scientist specializing in hematology, solid tumor oncology, and biomarker discovery.

LinkedIn
Shyam Sarikonda
Shyam Sarikonda, PhD
Advisory Board Member

Immunologist and biomarker development leader with 15+ years advancing cell therapies and immuno-oncology.

LinkedIn
Program progress

CCR8 preclinical focus

Lead immuno-oncology program positioned around CCR8 biology, TME modulation, and solid tumor relevance.

Grant support

BIRAC-BIG supported work

Next-generation antivenom development supported by BIRAC-BIG, strengthening non-dilutive validation.

Platform

PrecinAb™ + OptinAb™

Complementary AI/ML and experimental discovery engines support precision antibody design and optimization.

Partnering

Strategic collaboration ready

Open to licensing, co-development, investment, and oncology-focused partnership discussions.

Strategic partnerships & investment

Seeking strategic partners for MGX-101, including licensing, co-development, and investment opportunities

Out-licensing

Partnering opportunities around therapeutic and diagnostic antibody programs.

Co-development

Collaborations to accelerate IO assets and complex-target antibody discovery.

Strategic investment

Investment to advance the lead CCR8 program and scale discovery platforms.

Our Current Partners
AIC-CCMB
BIRAC
MSME
MST
CCMB
CDFD
Headquarters

4th Floor, AIC-CCMB

Hyderabad, Telangana, India, 500039

Connect

[email protected]

+91 73 82 700 600